Sodium thiocyanate also called sodium sulphocyanide, is the chemical compound with the formula NaSCN. This colorless deliquescent salt is one of the main sources of the thiocyanate anion. As such, it is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals

Sodium thiocyanate is employed to convert alkyl halides into the corresponding alkylthiocyanates. Closely related reagents include ammonium thiocyanate and potassium thiocyanate, which has twice the solubility in water.

Sodium thiocyanate (NaSCN) is normally used as a kind of food preservative in daily life, but using excessive NaSCN in milk would cause the low absorption of iodine in human body, and then would make the normal secretion of thyroid hormone disorder. In this study, we developed a method combines AgNPs and MIL-101(Fe) which is a kind of Metal organic frameworks materials as a kind of composite Surface Enhanced Raman Scattering (SERS) substrate and achieved the determination of NaSCN in spiked milk.

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