P HYDROXY ACETOPHENONE FOR SYNTHESIS
RXSOL-60-6605-252Hydroxyacetophenones are conveniently converted into the corresponding 1,3- dioxolanes by treatment with ethanediol and tri-isopropyl orthoformate in the presence of catalytic cerium triflate,
Product Description
Application & Usage
4′-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
Notes
Four chalcones derivatives have been synthesized from 3,4-dimethoxybenzaldehyde and acetophenone derivatives (2-hydroxy acetophenone, 2,4-dihydroxy acetophenone, 2,5-dihydroxy acetophenone and 2,6-dihydroxy acetophenone). The synthesis of these chalcones were conducted by Claisen-Schmidt condensation using grinding techniques at room temperature in the absence of solvents.
Other Names
P HYDROXY ACETOPHENONE FOR SYNTHESIS
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